Sialidase inhibition to increase platelet counts: A new treatment option for thrombocytopenia

Sialidase inhibition to increase platelet counts: A new treatment option for thrombocytopenia.

Finally, we did not detect a specific gene expression signature for GATA2 mutated vs. non-mutated cases. Overall, CR was achieved in 113 patients (88%), of whom 36 relapsed (estimated CIR at 3 and 5 years, 39%). Neither age nor karyotype or gene mutations (including NPM1, FLT3, of GATA2 and type CEBPA mutation) significantly influenced CIR in multivariate analysis. Five-year OS was estimated at...

a new approach to credibility premium for zero-inflated poisson models for panel data

هدف اصلی از این تحقیق به دست آوردن و مقایسه حق بیمه باورمندی در مدل های شمارشی گزارش نشده برای داده های طولی می باشد. در این تحقیق حق بیمه های پبش گویی بر اساس توابع ضرر مربع خطا و نمایی محاسبه شده و با هم مقایسه می شود. تمایل به گرفتن پاداش و جایزه یکی از دلایل مهم برای گزارش ندادن تصادفات می باشد و افراد برای استفاده از تخفیف اغلب از گزارش تصادفات با هزینه پائین خودداری می کنند، در این تحقیق ...

A new delivery model to increase adherence to methadone maintenance treatment

Eltrombopag: a new treatment option for chronic refractory adult immune thrombocytopenia

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Chronic immune thrombocytopenia (ITP) is an auto-immune disease characterized by immune-mediated platelet destruction and reduced platelet production caused by antiplatelet autoantibodies, leading to a marked decrease in platelet count and rarely life-threat...

Neonatal alloimmune thrombocytopenia due to a new platelet-specific alloantibody.

An infant with severe neonatal alloimmune thrombocytopenia is described in whom an antibody directed at a new platelet-specific alloantigen, Ca (HPA-6b), is implicated. The new alloantigen is of low frequency in the population and was localized to platelet glycoprotein (GP) IIIa. Immunoprecipitation studies using murine monoclonal antibodies specific for the GP complex IIb-IIIa and GPIIIa alone...